Printout from Pearl Cohen Zedek Latzer Baratz

Biography

Dr. Dror Shiftan is a Patent Agent in the Patents and Life Sciences Groups at Pearl Cohen’s Tel Aviv office. Dror focuses his practice on matters before the Israel Patent Office in the areas of pharmaceuticals, chemistry, and biology. Dror has also handles non-infringement and invalidity analysis involving pharmaceutical formulations, active compounds, and processes for preparing active compounds.

Dror is highly experienced in solving the three-dimensional structure of molecules, liquid and solid-state NMR, computer modeling and X-ray analysis, medicinal chemistry and rational drug design, polymer chemistry, and polymers as excipients for drug delivery.

 

Admitted

  • Israel Patent Office

Education

McGill University, Post-Doctoral Fellowship - Chemistry, 2000

Ben-Gurion University of the Negev, M.Sc. and Ph.D. Chemistry, 1998

Ben-Gurion University of the Negev, B.Sc. Chemistry, 1992

Languages

English & Hebrew

Publications

Glaser R, Shiftan D, Drouin M. Eight-membered ring conformations: The interconvertion of the solid-state conformations of retronefopam hydrochloride and deoxynefopam hydrochloride into those exhibited by nefopam hydrochloride, a non-narcotic analgestic drug. New J Chem. 1994;18:973. 

Glaser R, Shiftan D, Drouin M. The stereochemistry of a nine-membered ring analogue of nefopam, a non-narcotic analgestic drug. Struct Chem. 1995;6(1):25-35.

Glaser R, Adin I, Shiftan D, Shi Q, Deutsch HM, Wu KM, Froimowitz M. Solution and solid-state conformational and structural analysis of the n-methyl derivatives of (+/-)-threo-methylphenidate, (+/-)-erythro-methylphenidate, and (+/-)-threo-p-methyl-methylphenidate hydrochloride salts. J Org Chem. 1998;63(6):1785-94.

Glaser R, Shiftan D. The stereochemistry and interconvertion of nine-membered rings containing one strong torsional constraint. Adv Mol Struct Res. 1999;5:89-151.

Glaser R, Shiftan D, Drouin M. Conformational pseudopolymorphism and solid-state CPMAS NMR studies for determination of solvent-dependent solution-state conformational preferences for (-)-scopolamine hydrobromide/hydrochloride salts. J Org Chem. 1999;64(25):9217-24. (Additions and corrections: ibid. 2000;65:1898).

Glaser R, Shiftan D, Froimowitz M. NMR structure determination of brefeldin-A, a 13-membered ring fungal metabolite. Magn Reson Chem. 2000;38(4):274-80.

Glaser R, Shiftan D, Drouin M. The solid-state structures of (-)-scopolamine free base, (-)-scopolamine methobromide, (-)-scopolamine hydrobromide trihydrate, and of the pseudopolymorphic forms of (-)-scopolamine hydrochloride anhydrate and 1.66hydrate. Can J Chem. 2000;78:212-3.

Lebail P, Buleon A, Shiftan D, Marchessault RH. Mobility of lipis in complexes of amylose-fatty acids by deuterium and 13C solid-state NMR. Carbohydrates Polymers. 2000;43:317-26.

Shiftan D, Ravenelle F, Mateescu MA, Marchessault RH. Change in the V/B polymorph ratio and T1 relaxation of epichlorohydrin crosslinked high amylose starch. Starch. 2000;52:186-95.

Glaser R, Novoselsky A, Shiftan D. Eight-membered-ring solid-state conformational interconversion via the atom-flip mechanism, a CPMAS 13C NMR and crystallographic stereochemical study. J Org Chem. 2000;65:6345-53.

Glaser R, Shiftan D, Levi-Roso G, Ergaz I, Geresh S, Drouin M. cis-Cyclononene conformational families and a crystallographic example of a skew-chair[bond]boat type-2 conformation. J Org Chem. 2002;67:5486-96.

Co-developer and co-author of first Drug Design courseware, Molecular Conceptor Learning Series, at http://www.drugdesign.com/web/ (Version 1, 2002 and Version 2, 2004).